Thank you so much for your quick reply, I am in the US but am originally from Ireland. So glad that your lymphocytes are almost normal again. Have you noticed if Mavenclad has helped with the symptoms and or progression? Do you have to take the second years dose exactly a year apart or can you wait 13 months? I ask because I want to travel to Europe next August for a wedding and would not be able to do so if I start now.