I sort of did. I went from Tysabri to Gilenya and now to Clardribine. Switched from Tysabri for the same reason, JC+and was sad to move on as it kept me quite stable for about 5 years. Gilenya was also pretty decent, doesn’t have any relapses, but my liver enzyme results why through the ceiling while on it so I was offered some alternatives, Mavenclad or Lemtrada.
I’ve now finished year two of Mavenclad and have no reason to complain at all. No relapses while on it so far, only side effect was a dip in fatigue levels while taking it. I did however have a rebound relapse while flushing out the Gilenya, but I’d say it was worth it 🙂