I have been diagnosed with RRMS for 25y now. I have had steroids, Beta-interferon (Rebif), Glatiramer Acetate (Copaxone) and now Dimethyl Fumurate (Tecfidera) from the DEFINE trial onwards. I take high dose prescribed Cholocalciferol (Vitamin D3) 10000iu every other day in order to keep a level in …

DEFINE is the name for the long running Tecfidera (Dimethyl Fumurate) trial. You won’t be on it by accident so there is nothing of interest if you are presecribed Tecfidera by your neurologist. There is nothing to be concerned about if you aren’t on the trial. However, if you are on the…

One of the scariest side effects of ms dmts is pml. This article seemed pretty exciting and didn’t seem to make the news much so I thought I would post it here. Given how serious and rare it is not sure what kind of trial would be needed. I hope to find out more because if anyone gets this…

Right guys, sorry if this is too obvious but in this article i read ….some patients in original group continued to get worse early on after transplant, he added, “but we think that was due to previous disease before the transplant. There can be an early degenerativer phase, but that le…

MedDay Pharmaceuticals is developing high-dose pharmaceutical biotin for treatment of progressive forms of MS. Currently in phase III development, there is an ongoing clinical trial in Europe and the US named SPI2. Some articles I’ve read argue that this treatment can stop progression and has…

If you are Secondary Progressive MS (SPMS), between 20 and 65 with an EDSS of between 4.0 and 6.5, then this trial may be for you. Details here :- https://www.ucl.ac.uk/ion/research/centres/queen-square-multiple-sclerosis-centre/ms-clinical-trials/ms-stat2-trial