@ks

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ks

Booze

Hey, was just wondering how alcohol effects fellow MSers?! xx

cameron

@cameron

Fortunately it doesn't.

polly2311

@polly2311

I find if I've had quite a lot to drink the hangover the next day goes to my legs - I mean they really ache and feelheavy and it gets better as the general hangover wears off.

DJDsouza

@DJDsouza

Beer used to make me need the toilet after a couple of pints. Now, with MS, a little bit triggers off my bladder urgency - so half a pint :( Hopefully the treatment I'm having for bladder urgency will allow me to enjoy it a bit more in a few months ;) (Though, I don't really enjoy the delayed reaction effects of drinking, so maybe not!)

jman

@jman

Probably some medications that react to booze, or other juices. I don't know MS meds, but some drugs change their absorption rate with grapefruit, starfruit,hmm trying to think of the other one:)

DJDsouza

@DJDsouza

I think with me, it's a combination of old age, and the MS as I'm not on any medication

ichope

@ichope

I do enjoy :). I agree with Polly2311 in that it goes straight to my legs. We give up enough! Looks like "Girls just wanna have fun"

rainyp

@rainyp

Hi I inject myself with copaxone daiy and take 2 pregabalina capsules. The 1st time a was drunk i thought that was the end!!! ;( luckily friends got me home in one piece ;)I do enjoy a drink, who doesn't??I no i just have too be happy with the 1 ;o Can i just say it was the 1st drunken night whilst takin medication, not in my life, lol

chueykooh

@chueykooh

I have drank in the past quite heavily when I had only sensory problems and I must say that it helped me. I have a slight limp in my left leg and after a couple of drinks, my friends would notice I would walk straight as an arrow and felt better overall, with my recent flare up which affected my speech, and motor skills somewhat, and is accompanied with dizziness and cognitive issues so I haven’t drank at all. I already seem a little drunk, lol. So I guess it depends on the person and the symptoms. I also started LDN last night and am a little worried about trying any alcohol right now because I have heard horror stories about mixing LDN and alcohol, but you never know.

namansareen88

@namansareen88

I was on Lyrica some time ago...went to a friend's for new years and drank quite a bit...was happy high! Then we're watching TV and I just sorta slid into unconsciousness out of the blue....one minute I'm talking and laughing, the next second everyone staring at me and slapping me trying to wake me up. Someone actually started checking my pulse to see if I was alive! After 10 minutes of this I apparently woke up with my hands up telling everyone to back off, absolutely no idea about what had happened! That was my one close encounter with meds & alcohol...

eMarshallZo

@eMarshallZo

i know if am going out on the lash with my friends i have to sleep before hand or i will not even last till 1am! i sleep for ever the next day and my legs like to give up on me feeling heavy.

Aoife

@Aoife

I get quite tired, so I usually nap before I go out, and the next day I feel a bit weak and wobbly, but it's only for the one day every now and again so I don't mind!

carolyn22

@carolyn22

I feel like crap for a week after a good nite out!!!!! But....... I still do it!! You gotta live! Lol x

rainyp

@rainyp

I know it was Lyrica that effected me when out boozing, only cause i read the info about it too late!!!

pottypete

@pottypete

Bonus! Stagger in to a pub and walk out. Can't be anything wrong with that.

chueykooh

@chueykooh

@ pottypete, that's funny! I never thought about it that way. lmao

rochelle28

@rochelle28

Drinking just my legs feel heavy anymore.... no fun but I still do it when I have a babysitter lol :)

loulou

@loulou

Hi there Potty Pete, I was wondering where you were! not heard from you for yonks! I do hope you are well, Ive requested friendship as I woudn't mind having a chat with you about something

reddivine

@reddivine

Any meds and booze is prob not a good idea...as evidenced by the above stories. The effect is gonna vary with the person, the meds, whether you eat at the same time...... Personally I NEVER get blotto, but thats cuz the meds i am on for epilepsy plus booze send me sleepy......2 glasses of vino and I'm under the table. Plus I'm with DJDsouza.....frequent trips to the loo do nothing for yr social life.

highheeledfagin

@highheeledfagin

It doesn't that much anymore, other than sometimes just feeling that another drink is going to end badly. It took twisting an ankle four times and breaking my nose for me to realise that two drinks was guaranteed to get me to the point that a whole night's worth of drinking might not even get me to. The booze seemed to specifically target whichever major symptom was currently bugging me: originally, having a bit of a drink and a dance would set of my tonic spasms without fail, and when I started having problems with my leg and balance, it switched to that. I stopped drinking for two years, steadily made my way back to social drinking, had to stop again, and now I'm okay with drinking with mates in my house as not much can happen to me here, but rarely have more than one when out.

highheeledfagin

@highheeledfagin

At an MS information day at the NHNN in London, I asked the specialist why alcohol affects MS, and he just said "does it?".

DjBlack

@DjBlack

After a solid night on the booze ... I think it is more the lack of sleep that kicks my arse for the next few days til I catch up. Other than that I have a right royal time haha. Just gotta make sure I have a decent feed before ... and a kebab on the way home haha

lloyd

@lloyd

I like to down 10 beers on a Friday or Saturday night and I can almost walk normal go figure, and when I'm straight I drag my left leg. I probably need to drink 7 days a week but less quantities. If I drink certain beers I will get an instant headache but I like Beck's not headache or hangover good beer.

lightningduck

@lightningduck

I guess it's one of those "everybody is different" things I notice I get drunk faster which enhances but is sometimes disguised by a tendency to wobble when I walked anyway

lorag

@lorag

i have cut down on alchol espeacilly wine ,i have to run to the toilet after one and have had some very very embarrassing moments thank goodness nobody saw. my legs ache too, i have just gotten to the point of thinking is it really worth it. I'm a happy talkive person without alchol anyway, its more of a social thing at my work on fridays but just gotta say NO. ha ha

lorddaresbury

@lorddaresbury

In my experience either two shorts , a couple of glasses of champagne or a couple of beers actually improve my mobility. Cheers, Prost Cin Cin, Nick

funnybank

@funnybank

sometimes i really miss alcohol then other times i remember the hangovers and throwing up and saying wholly inappropriate yet hilarious things to people. i have the odd swig of weak beer and a chocolate cherry liqueur. but alcohol absolutely ruins me physically and mentally, i think i've been more or less sober for 7 years.

Gav

@Gav

<a href='https://shift.ms/community/people/funnybank/' rel='nofollow'>@funnybank</a> You don't need alcohol to make wildly inappropriate comment, or at least I don't ;-) As far as the drinking thing goes for me, I'm not a big fan personally. I've never had a hangover, but then I don't drink enough to warrant one (I have one, two drinks tops)

Stumbler

@Stumbler

I came to a decision may years ago that alcohol's cons really outweighed its pros. I mean:- - it costs a lot, especially these days; - it can make you ill that night; - it can make you feel terrible the next day; and - it allows you to say and do things that you shouldn't. Now, I'm not saying don't go out and socialise. Go out and have non-alcoholic drinks. Then you can watch all the others making fools of themselves! Anyway, I can't walk in a straight line when I'm sober! :)

carolyn22

@carolyn22

I still enjoy my red wine, don't really get hangovers unless I drink after my infusion can feel a bit rough!!! Defo the walking thing does work, I can walk with high heels on and not fall down if am under the influence!!! Lol! xx

RichMurray

@RichMurray

All this information by MSers about the complex effects of booze are really valuable information, full of hints about the probable initial cause of MS... Dark wines and liquors (fruit brandies are the worse) can have high levels of methanol (wood alcohol), 50-150 and more mg/L -- humans only of all mammals have no natural catalase defense against the ADH1 enzyme quickly turning blood methanol into formaldehyde inside the cells of the middle walls of blood vessels at the base of the brain, right where the initial lesions of MS form -- but the ethanol is an antidote that stops this methanol/formaldehyde toxicity (used in hospitals to treat methanol toxicity) -- however, the ethanol falls by half every 20 minutes until it is gone, leaving the ADH1 enzyme free to start making the residual methanol into formaldehyde, the major cause of alcohol hangovers "the morning after the night before" -- this is why many chronic diseases are worse for people who never drink alcohol, compared to those who drink alcohol only a little, a mystery found by many teams the last decade -- there's quite a lot more to all this, according to Prof. Woodrow C. Monte, who gives on his website WhileScienceSleeps.com 745 free full text medical research references, along with a free chapter on MS from his text "While Science Sleeps" -- other main methanol sources are cigarette and wood smoke, aspartame, and fruits juices vegetables preserved wet at room temperature in cans jars plastics -- still controversial, the paradigm is starting to be discussed -- Monte has free videos of 4 talks since 2010 to the Southland MS Society in New Zealand -- I want to alert people, without becoming a pest... RichMurray

StallionicChampionic

@StallionicChampionic

mmm it's definately saying, don't drink if you've been taking Lyrica!! I'm on LDN and that's not too clever if you've had a skinful. Otherwise i'm like alot a people, stagger into the pub and walk out.......well walk after 3-4 pints!! I find too my hangovers take days to get over and i'm very heavy legged the next day!!

tonyb

@tonyb

I like drinking. When my legs are wobbly I can blame the alcohol and I forget the MS :)

loulou

@loulou

Yes I enjoy a glass of wine in the evening but I have vowed this morning to give it up in favour of a G&t or similar, I dont know what it is but wine has been making my legs awful the next day, really stiff ! its also full of calories so best off without it I reckon

tonyb

@tonyb

Hmmm. Having posted that last comment something I noticed It's 11:00 pm here in Sydney., I've had a really bad day with my left leg. Couldn't lift it, dragged it around all day I just went to get a Beer (having had a few already). Guess what ? My left leg has decided to work again :)

zoom

@zoom

Being a man of few hobbies, wine is definitely top of the list, collecting, storing and most importantly drinking as my inability fill my cellar testifies (more drinking than buying). I'm with <a href='https://shift.ms/community/people/Stumbler/' rel='nofollow'>@stumbler</a> on one count, it is not worth drinking cheap wine...no upside! Hangovers milder if not nonexistent and given it's more expensive you can't really drink yourself silly. More technically better wines will have typically less methanol. Now I need to rethink my intake of diet and coke zero, if aspartame is an issue, hadn't noticed that yet, this where I get my caffein pick me up in the afternoon as I do not drink coffee.....hmmmhmmmm

RichMurray

@RichMurray

yeah, aspartame (E951) is 11% methanol -- one diet drink has 200 mg aspartame, with 22 mg methanol -- huge individual variations in vulnerability -- so check out your own experience carefully -- now, many people have beneficial bacteria in the gut that make enough ethanol to prevent the ADH1 enzyme from making methanol into formaldehyde right inside cells in 19 specific tissues -- drinking small amounts of low methanol alcohol drinks is known to result in fewer symptoms from many chronic diseases than never drinking at all -- a research mystery that is explained by the methanol formaldehyde paradigm of Prof. Woodrow C. Monte www.WhileScienceSleeps.com -- anyone here notice problems with aspartame?

zoom

@zoom

I suspect it is one of those things that would turn psychosomatic, I hadn't noticed any issue with aspartame before and I consume 2 or 3 cans a day of some diet soda variety. Now that I know about it every little tingle and itch will now be attributed to that..... One more thing to have to let go off. So is plain old sugar good now?!

RichMurray

@RichMurray

Hi Zoom, I've seen plenty of health complaints on the Net for 13 years about sucralose, but none at all about stevia, except some dislike its flavor -- so I buy stevia as little bottles of white powder, and use about 1 or 2 tiny spoons (1/8 inch wide) per cup tea -- sometimes I use a packet or a half-teaspoon of regular sugar -- seems really sweet to me, having lost interest in soda pop -- another type of drink to worry about is any fruit juice (tomato, orange, grape, grapefruit, ect.) preserved in cans jars plastics -- fresh uncooked juices and fruits kept frozen are OK, while even fresh tomato probably has too much methanol for MSers -- best for each person to stay alert to their own experience -- also, really good policy to avoid all chemical food additives (preservatives, MSG, dyes) -- www.forksoverknives.com -- I pay attention to ears ringing, drowsiness, irritation, confusion, allergies, sneezes, headache, skin rash, as clues I recently took in something harmful. within mutual service, Rich

lightningduck

@lightningduck

<a href='https://shift.ms/community/people/RichMurray/' rel='nofollow'>@RichMurray</a> I've been using Stevia for a few years now; the taste does take a but to get used to but if you believe in it, you can adjust. Yeah, it's fairly concentrated so I just use a few drops in my coffee Great stuff :)

zoom

@zoom

That's very useful guys, I've been recently diagnosed, and I think I will need to overhaul my diet.... Do you think it is worth talking to a nutritionist and are there some who specialise in MS? It could be something the MS nurse helps with, I've not signed up for that yet as I've been doing everything privately.... Expensive but I can't deal with the NHS wait times. I've seen my Neuro who works both for the NHS and on the side in a private clinic like 6 times in the last 3 mths, done 5 MRIs over the last year and every test under the sun in a month. He even wanted a 2nd opinion from an NHS only professor and I got an appointment within 2 weeks, none of that wait 3 mths wait nonsense, that's why a lot of us remain undiagnosed for so long and get stressed out about which is major cause for relapses, what a sled defeating system!

cameron

@cameron

The MS society has several publications. The MS nurses were helpful but have the 'mainline' view, which is to have a normal healthy diet with as little animal fat as possible. If you want to go more extreme, there is a lot of info on the MSRC website. They advocate the 'Best Bet Diet', which is basically cutting out dairy and animal fats (I think!). Then there's all the supplements you can take.... I've said this already in other posts but it's worth re-stating, I asked the neuro about special diets and he told me that yes, I might feel better but no, it wouldn't affect the disease course. He told me he was quite sure about it (because I asked him again!). As he's a leading MS researcher, I did believe him. Making changes in your diet isn't easy but I guess it's part of coming to terms with MS and deciding how you want to live your life. Like you, I toyed with the idea of a nutritionist. Didn't do it in the end but did get tested for food insensitivities through the York Test (google it, it's a home blood test which you send off for analysis). Nothing came up so in the end I just carried on as before, but I try my best to be healthy.

mmmark

@mmmark

I'm on Rebif 3 times a week and take it on a Tue/Thur/Sun schedule just so I can have Friday and Saturday to be able to drink beer. That sentence totally makes it sound like I sit in a chair with a case of beer and go to town on it haha. That's not it at all, but I do like to have a few beers now and again. I love beer. Used to drink more of it, but I do get the heavy legs the next day. Also, I brew my own beer and have started customizing recipes. I wonder if I can figure out an MS friendly recipe that magically repairs myelin. Beer would be the most amazing way to cure a disease. I'd look forward to taking my medicine then!

tiltawhirl

@tiltawhirl

My wife and I aren't really big drinkers, but I have noticed my booze tolerance has gone down over the years as the disease has progressed. I avoid hangovers by just smoking pot instead. :) tilt

StallionicChampionic

@StallionicChampionic

went for a meal on Sunday and had too much to drink.........still feeling it now, fatigued, can't be bothered, heavy legs etc. Still was a good day though!! seem to be at the stage now where i stagger into a pub and have to be carried out rather than walk out!!

RichMurray

@RichMurray

hits on WhileScienceSleeps.com jump 72.5 times from 1,751 to 127,009 on Sunday November 11, due to video interview transcript, Woodrow C. Monte shares aspartame methanol formaldehyde toxicity paradigm with Joseph Mercola: Rich Murray 2012.11.12 http://rmforall.blogspot.com/2012/11/hits-on-whilesciencesleepscom-jump-725.html Interview with Prof. Woodrow C. Monte, methanol formaldehyde toxicity paradigm, 33 page plain text September 2012 Joseph M. Mercola DO: Rich Murray 2012.11.11 http://rmforall.blogspot.com/2012/11/interview-with-prof-woodrow-c-monte.html "I want to talk with people with MS or people who know somebody with multiple sclerosis. That case has, I think, actually been proven for me. There was actually research done that looked at the parts of the brain just outside of the plaque areas and they searched for changes, and they found changes. They didn’t know why the changes had occurred, but the two changes that occurred were extremely important. This was done about seven or eight years ago. The two changes that occurred was one, an increase of methylation and an amino acid that is known to basically store formaldehyde and to be changeable by formaldehyde. They found that, and they found a tremendous decrease in -- I will call it phosphorylation, but it’s the same mechanism that would be used to producing ATP. Those are the most important and really the only major changes they found in that tissue. If I were to design a study to see if methyl alcohol were to cause that damage, that’s exactly the study I would have designed. I would have done it exactly that way, and I would have looked for those exact changes. That’s what you have to look for. You cannot find formaldehyde in the human body after it’s been even injected in the human body. It disappears. You’ve got to look for the changes that it causes -- the shadow of formaldehyde. That is the shadow of formaldehyde. They have already found it in people with multiple sclerosis. http://www.whilesciencesleeps.com/pdf/224.pdf 224. Kim J, Mastronardi F, Wood D, Lubman D, Zand R, Moscarello M. Multiple Sclerosis: An important role for post-translational modifications of myelin basic protein in pathogenesis. Molecular & Cellular Proteomics 2003;2(7):453-62. I say that disease has been solved. I know I’m brazen saying that. I’m sure enough to say it. I’m sure enough of the fact that the recommendations I’m making to change your diet is so safe that you’re risking your life by not making those changes. Make those changes if you have multiple sclerosis. I’ve done it in New Zealand. I’ve done it with Cori Brackett. I’ve done it with people who have multiple sclerosis. I’m not saying a lot of people, but everyone who has tried it has definitely seen an amazing improvement. If you don’t have any improvement, email me through my site and tell me what you’re eating. I’ll take a look at your diet, because I think it’s going to work. http://whilesciencesleeps.com/files/Monte%20Diet.pdf DM: That’s a kind offer. I would add to that -- and it’s something you already know -- expose as much of your skin to sunshine or a safe tanning bed if it’s in the middle of winter. DW: Definitely. DM: You need that energy into your system. DW: To rebuild the myelin. DM: And probably for a variety of other things. It’s the combination of the two. Of course, eating a healthy diet -- I’ve got a whole nutrition program that goes into that and exercise. But really, the key especially for these serious autoimmune diseases like MS, which is probably the most serious and can be deadly…. It kills so many people, if not cripples them for life. It’s just a really sad and tragic disease. It just doesn’t make sense not to try the simple basics." pack cigarettes gives same methanol as liter aspartame diet drink, 60 mg, which ADH1 enzyme makes into highly reactive acidic hydrated formaldehyde inside cells of blood vessel walls at base of brain, perivascular loci for first MS lesions: Rich Murray 2012.11.12 This explains why people who never drink suffer more from many chronic diseases than those who drink about one alcohol drink daily - Ethanol (ordinary alcohol) prevents harm from methanol (wood alcohol) sources, including many dark wines and liquors - aspartame (E951) - smoke from wood peat cigarettes - fruits juices vegetables, sealed wet in cans - fermented smoked spoiled foods - fresh tomatoes, black currants - jellies jams marmalades - some fresh coffees - chewing gum (often have aspartame) - bacteria in the colon - genetic flaws in metabolism - vehicle fumes - processed wood products of all kinds - factories making leather, paper, particle board and plywood, or using solvents - mobile homes - As long as ethanol is in the blood, the ADH1 enzyme is preempted from turning methanol into formaldehyde right inside cells in 19 specific tissues - WhileScienceSleeps 745 free online full text medical research references by Prof. Woodrow C. Monte, Food Science and Nutrition, Arizona State University, retired 2004.

msue62

@msue62

I like a glass (or bottle) of wine occasionally. It makes me forget this awful thing I have and at the moment it makes me walk better. Sometimes I do zone out totally but I come back quickly. I wouldn't do it too often and the hangovers are worth it but I will be watching myself carefully to see how my symptoms go. ★