Hi @lisaneighbour I started Tysabri in November 2017. To begin with I was dreading it...6 months on I really don’t know what I was worrying about. Yes, having to go into hospital every 28 days is slightly frustrating but the way I think about it is that I am able to see my MS nurse, if needed and I get a couple of hours each month that I can dedicate to a good book (hubby bought me a Kindle -fab!) I have recently had a MRI which, for the first time in goodness knows how long, shows no progression. Hope this has helped -good luck with whatever decision you make. Cat x

Hi Ive just had my 11th infusion. I was a little bit nervous before I started, as my blood tests came back as JCV +. Despite this my doctor persuaded me to go ahead as my level was low. The infusion itself is pretty straight forward. When you arrive the nurses will check your obs and test your urine. The drip will be set up and will last an hour. You will then wait a further hour to check you dont have a reaction. Then you can go home. So far I have experienced an increase in my leg and arm pain and have felt very anxious. I had both of these symptoms before and they have got a little worse. I know from speaking to others at hospital, that they have not had any problems to speak of and i am still working and doing everything I was doing before, therefore it seems to be very well tolerated. Sometimes i feel sleepy when im having the infusion. I always drink plenty of water while im there too. I hope everything works out well for you. Sarah