@Someone 

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Someone

Tecfidera ramp-up cramps

Hi everyone, I started with Tecfidera 3 weeks ago, first 2 x 120 mg a day for two weeks. I was completely fine except for blushing (which I don't find that disturbing) and even that seemed to be more drastic in the beginning. When I moved to 2 x 240 mg I got the most severe stomach pain after 2 days. I had to go to the hospital because the pain was so intense and I was worried because the list of side effects does have some nasty liver & kidney things as well. Everything was okay, they told me to stop taking Tecfidera and the next day I called my doctor to see what we should do with the meds. She suggested a new ramp-up but more slowly: 2 x 120 mg for two weeks, then for two weeks 120 mg in the morning and 240 mg in the evening, then to full dose 2 x 240 mg. I'd be happy to hear about someone who has succeeded with Tecfidera but not on the first go. What did you do differently? I'm super motivated to get the meds right but I haven't felt this intense pain in my life. Also, has anyone had fever when they started Tecfidera? I'm wondering if this is related or do I just have a regular flu on top of this. I've already gotten really good advice from here, like taking the meds mid-meal and taking with a probiotic. My doctor told me fatty foods are good and recommended to take some cod liver oil which is commonly used here in Finland as a dietary supplement 😝
@Lowlander

@Someone Hi it should calm down after a couple of weeks or so, just make sure you take it with food.

@Someone

Update: after a really intensive 48 hrs the cramps finally seem to be going away... phew!