Dear all, Some of you may recall me, although I have not posted regularly of late. I have seen a variety of posts debating the availability or lack thereof of aHSCT outside a trial setting. Just to clarify, it; 1. Is available on the NHS 2. Is subject to fulfilling a strict criteria determined by your referral by your own GP or neurologist to the requisite neurologists in London; pls see link below 3. Is thereafter, subject to approval by a board of neurologists and haematologists who rule upon each case advanced to them. 4. If rejected at the outset, it is possible to put one's case forward again should circumstances change e.g MRI inflammatory lesions/failure of certain high efficacy DMDs etc 5. This is completely unrelated to the Sheffield trial which may sometimes consider on compassionate grounds 6. There are a multitude of other options available in countries including Russia, 2 in Mexico, Singapore, Chicago, Israel, India etc etc 7. This is a high (debatable) risk procedure, with some centres having higher incidences of issues than others so research carefully! 8. Kings plus Hammersmith are the London treating centres 9. The treatment criteria favours the young and relatively newly diagnosed with RRMS, but has worked successfully in SPMS and PPMS, although it is often far more stringent a process to satisfy the UK criteria in this regard, although this is not the case abroad 10. Different centres abroad treat patients with a higher EDSS 11. The centres abroad have often lengthy waiting lists, so if interested, it is advisable to contact the relevant centre and request your name be placed on the list. No money is required as a deposit at this stage. Some can be over a year or two so provides ample opportunity to attempt to raise the requisite funds if unsuccessful in the U.K. Again, some countries may treat earlier on compassion grounds. 12. There is talk of a possible further clinical trial in of HSCT v drugs for newly diagnosed patients, but this had yet to be decided. The link referred to in number 2 is below: http://multiple-sclerosis-research.blogspot.com/2016/01/london-ms-ahsct-collaborative-group.html?m=1 Good luck! Monica