So my wife of 31 years was diagnosed with RRMS in 1995. In that time she has tried many many medications. Nothing has stopped or even slowed her progression into secondary progressive MS. We travelled to Poland 2010 for CCSVI treatment. Still her MS progressed. She has been using a wheelchair now for 15 years. At first she only used when going long distances. Slowly over time she needed it more and more. Now she can no longer stand or even transfer from chair to bed or toilet. She has remained so strong for all these years it really is a testament of her inner strength. Now for the toughest question of all, her bowels are now starting to shut down. There seems to be nothing that helps. Does anyone know of this as a complication of MS? I don’t think there is anything that can help her. Any information would be greatly appreciated. Sorry for dumping all this on my first post but I don’t really have anywhere else to turn!