@Adiba24 

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Adiba24

Shifting from Tysabri?

Hey guys, I’m new here. I was diagnosed with MS when I was 19 in 2018, and have been on Tysabri since because my JC virus was negative. Now it has become indeterminate and we have to switch to another medicine. Has anyone here done this? How was your experience and what did you switch to? And did anyone switch to mavenclad - cladribine ?) I know it’s a lot of questions but I’m a little worried and would love any help and input ❤️❤️❤️
@Chrbea0329

Hey I'm new here too. I was diagnosised in 2019 but I've had it for 15yrs. I was put on Ocravus infusion, twice a yr. I wouldn't know about any other meds but Ocravus does good for me

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@londonlad

Hi @Adiba24 I took Tysabri for 4 years and it was great at keeping things stable. I turned positive but stayed on the medication for a bit longer as the level was low, and they changed me to 6 weekly schedule which reduces the risk of PML. However, eventually I was keen to change, not only for the above risk factors, but also, I planned to move to one of the medications (IRT) that don't need frequent administration. More for lifestyle choice and ease of not having regular appointments. I explored the options and made the change to cladribine in 2021 and have recently just finished the second (and final) year. I am doing well (touchwood) and very pleased at my decision. I have had minor to no side effects. At most I have felt a bit more tired, and maybe headaches. But I cannot 100% associate them with the meds. I didn’t have a sustained washout period. I had my last Tysabri infusion, and I think I took my first cladribine around a month later. Best of luck